special case carcinogens are classified as genotoxic and non genotoxic genotoxic carcinogensare characterized by a no threshold dose response relationship there is some level of risk even if it cannot be directly measured at every level of exposure
Báo cáo khoa học: Assembly of collagen types II, IX and XI into nascent hetero-fibrils by a rat chondrocyte cell line ppt
Ngày tải lên :
31/03/2014, 07:20
... Iwata, M & Sandy, J.D (1995) Cell-mediated catabolism of aggrecan Evidence that cleavage at the ÔaggrecanaseÕ site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain ... [24] and by ADAMTS-2 (the known fibrillar collagen N-propeptidase) and ADAMTS-3 (the putative collagen N-propeptidase of cartilage) [25] The present results indicate that mature trivalent pyridinoline ... collagen from rat cartilage (upper panel) was resolved by reverse-phase HPLC as a control for comparison with the RCS-LTC digest (lower panel) Fractions marked by a bar contained a1 (II) chains, as...
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Báo cáo khoa học: "Stomatal and non stomatal limitation of photosynthesis by leaf water deficits in three oak species: a comparison of gas exchange and chlorophyll a fluorescence data" potx
Ngày tải lên :
09/08/2014, 03:24
... wp creases in A and g were steep, with higher rate initial values, but the overall evolution was Alteration of (A, C) relationships showed that apparently both stomatal and non stomatal factors ... limitation of A The maximal rate of net CO assimilation at high C (A was first af) i max fected According to von Caemmerer and Farquhar (1981) and Farquhar and Sharkey (1982), this could mean a ... the mean of replicates Gas exchange measurements Whole leaf gas exchange was measured in an open system designed in the laboratory Net COassimilation (A) and transpiration (E) rates were monitored...
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Báo cáo y học: "Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin" pptx
Ngày tải lên :
09/08/2014, 06:22
... reactive arthritis (ReA), psoriatic arthritis (PsA) and a number of miscellaneous conditions according to established criteria Of the 36 patients with non- crystal-related early inflammatory arthritis, ... patients with early non- rheumatoid persistent disease (one PsA, one ulcerative colitis related arthritis and three unclassified) and in three patients with early self-limiting disease (two ReA and ... significant; NSAID, nonsteroidal antirheumatic drug; RA, rheumatoid arthritis; RF, rheumatoid factor Results Patient characteristics Baseline characteristics of patients with early inflammatory arthritis...
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Báo cáo khoa học: "A comparison of dose-response characteristics of four NTCP models using outcomes of radiationinduced optic neuropathy and retinopathy" potx
Ngày tải lên :
09/08/2014, 09:20
... substantially deviate at doses beyond available clinical data (Figures and 3) Table lists the calculated model parameters and confidence intervals For the considered RION and RIRP data, log-logistic ... does not have to be quantitatively accurate as long as it ranks a radiobiologically more desirable plan higher than less desirable Use of biological models for plan ranking cannot be separated from ... Rudat V, et al: Evaluation of salivary gland function after treatment of head -and- neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy Int J Radiat Oncol...
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Báo cáo y học: "Extent of exposure to environmental tobacco smoke (ETS) and its dose-response relation to respiratory health among adults" doc
Ngày tải lên :
12/08/2014, 18:21
... indices of both exposures and outcomes We have some indicators that such bias was limited, including lack of associations between a diagnosis of asthma or chronic bronchitis and ETS score Remarkably, ... general (Table 4), as well as medical care utilization for a specific problem (e.g asthma, pneumonia, analysis not shown) In the univariate analysis, there was a weak inverse correlation between ... a study of 349 adults with asthma in the US, Eisner and colleagues found that exposure to ETS at baseline was associated with more symptom severity and emergency/hospital admissions because of...
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Báo cáo y học: " Site-specific dose-response relationships for cancer induction from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapy" ppsx
Ngày tải lên :
13/08/2014, 16:20
... + a ln agea 70 (2) In this form the fit parameters are gender-averaged and centered at an age at exposure of 30 years and an attained age of 70 years The initial slopes bEAR and the age modifying ... organ dose as long as the dose- response curve is linear At high dose it could be that the dose- response relationship is non- linear and as a consequence, OED replaces average dose to quantify radiation ... however that sarcoma induction at high dose is at a comparable magnitude than carcinoma induction Therefore it is not appropriate to assume a pure linear doseresponse relationship for sarcoma induction...
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Báo cáo y học: "Temporal and spatial patterning of an organ by a single transcription factor" pps
Ngày tải lên :
14/08/2014, 14:21
... experimental strategy used by Mango and colleagues [8,9] to identify regulatory motifs that specify temporal and spatial patterns of gene expression during pharyngeal development (a) RNA was isolated ... expression, either at a particular time or at a particular point in space, is specified by a unique combination of regulatory molecules and cis-regulatory elements These unique combinations are generated ... factors are shown at the top, and the promoters of four genes (A- D) that are expressed at different times during pharyngeal development are shown below EARLY1, LATE1 and LATE2 are the putative transcription...
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Magnetic domain study of micron and nano sized permalloy structures induced by a local current
Ngày tải lên :
10/11/2015, 11:34
... the basic operation of the MRAM structure Each MRAM data cell consists of a stack of magnetic and non- magnetic layers whose magnetic moment can be manipulated by an external magnetic field Arranged ... application 113 and removal of +2000 Oe saturating field in the easy axis Fig 6.26: OOMMF and MFM images of an isolated µm x µm rods after 114 application and removal of +2000 Oe saturating field along ... of an isolated µm x µm rod at critical 126 field values along the hard axis Table 7.1: Domain configurations of an isolated 800 nm x 200 nm rod at 139 critical field values along the easy axis...
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The importance of introducing some cultural aspects on stubborness of the british to sophomores of english majors and non english majors at hanoi pedagogical university no 2
Ngày tải lên :
30/11/2015, 09:14
... areas of land associated with farming, forestry and real estate are often advertised measured in acres and square feet, but for official government purposes, the unit is always hectares and square ... of England, Scotland, Wales and Northern Ireland Its full name is the United Kingdom of Great Britain and Northern Ireland Great Britain, on the other hand, comprises only England, Scotland and ... Australia, New Zealand, Canada, and parts of Africa, India, and many smaller island nations speak English English is the commonly adopted second language in Germany, Norway, Sweden, Denmark and...
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The a and b adapters are used as priming sites for both amplification
Ngày tải lên :
19/03/2014, 22:32
... Preparation of the DNA • DNA is fragmented by nebulization • The DNA strand’s ends are made blunt with appropriate enzymes • A and “B” adapters are ligated to the blunt ends using DNA ligase ... the wells not allow more than one ssDNA bead to be loaded into a well • Enzyme beads and packing beads are added Enzyme beads containing sulfurase and luciferase, and packing beads used only ... • The strands are denatured using sodium hydroxide to release the ssDNA template library (sstDNA) The Adapters • The A and B adapters are used as priming sites for both amplification and sequencing...
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Module V Viruses and Worms.Introduction to VirusComputer viruses are perceived as a threat to potx
Ngày tải lên :
31/07/2014, 04:20
... get loaded into memory and infect at later stages Attack Phase: • Some viruses have trigger events to activate and corrupt systems • Some viruses have bugs that replicate and perform activities ... is a Worm different from a Virus There is a difference between general viruses and worms A worm is a special type of virus that can replicate itself and use memory, but cannot attach itself to ... Lack of control • Difficulty in distinguishing the nature of attack • Draining of resources • Presence of bugs • Compatibility problems Ethical and Legal Reasons: • There are ethics and legalities...
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Báo cáo y học: "Adrenocortical carcinoma presenting as varicocele and renal vein thrombosis: a case report." ppsx
Ngày tải lên :
10/08/2014, 23:22
... of local unresectability and metastatic disease Mitotane, an adrenocorticolytic drug, was started at an initial dose of g/day and the dose was later increased to maintain plasma levels between ... compatible with metastasis Anti-coagulation therapy, a mg/day dose of warfarin adjusted according to International Normalized Ratio levels and five days of mg/ kg enoxaparin administered subcutaneously ... of men and are believed to be secondary to the venous anatomy of the left testis Rightsided varicoceles usually occur as bilateral processes and are apparent in 10% of clinical cases and in as...
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Báo cáo y học: " Cholangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia: a case report" ppsx
Ngày tải lên :
11/08/2014, 12:20
... literature J Med Assoc Thai 2001, 84(3):438-444 Bando T, Matsuoka J, Hashimoto I, Oonishi Y, Nozawa S, Yamagishi F, Tsukada K, Takahashi H: A case of bile duct carcinoma with Haemobilia Japanese ... Abdominal CT scan showing area of low attenuation in right lobe of liver ciency anemia and highlight the fact that colonic and gastric carcinomata are by far the most common malignant causes [6] ... report an literature review Ann Ital Chir 2008, 79(1):57-61 13 Apostolidis S, Papavramidis T, Zatagias A, Michalopoulos A, Papadopoulos V, Paramythiotis D, Harlaftis N: Hematemesis, a very rare...
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Báo cáo y học: "Water intoxication presenting as maternal and neonatal seizures: a case report" ppsx
Ngày tải lên :
11/08/2014, 19:21
... osmolality of 225 mosmol/kg The mother was subsequently managed on the intensive care unit and the baby on the special care baby unit A maternal lumbar puncture was normal as was subsequent cranial magnetic ... failure as a possible cause for the hyponatraemia and osteoporosis Parathormone and thyroid function testing was also normal The osteoporosis could be associated with the pregnancy, as no other cause ... the fetal plasma sodium level will mirror maternal hyponatraemia [5] The natural release of oxytocin hormone during labour with its similarity to anti-diuretic hormone (ADH) may also be a factor...
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Báo cáo y học: " Achondroplasia manifesting as enchondromatosis and ossification of the spinal ligaments: a case report" ppsx
Ngày tải lên :
11/08/2014, 21:22
... enchondromatosis and ossification of the spinal ligaments Case presentation A 7-year-old girl was brought to the orthopaedic department because of mild knee and back pain associated with restricted ... She was clinically and radiographically diagnosed as having achondroplasia This was confirmed through the detection of the common mutation of FGFR3 for achondroplasia The parents were of normal ... show metaphyseal cupping with multiple enchondromatous lesions and an abnormal metaphyseal trabecular pattern associated with small round rings and arcs and dense foci is as intended here within...
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Báo cáo y học: " Breast conserving surgery with preservation of the nipple-areola complex as a feasible and safe approach in male breast cancer: a case report" pptx
Ngày tải lên :
11/08/2014, 23:21
... syndrome), exogenous oestrogen administration and testicular anomalies are among the risk factors [1-4,6], while radiation, obesity and alcohol use are proposed but not widely accepted as risk factors ... survival [3,5,6,11,12] There is also a proven effectiveness in those patients with metastatic disease and, therefore, Tamoxifen has been incorporated in the treatment of MBC [2,3,5,11] There is not ... (IDC) Investigations did not show any distant metastases The patient was offered modified radical mastectomy and sentinel node biopsy (SNB) The patient declined any operation that would not preserve...
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báo cáo khoa học: " Traditional agroecosystems as conservatories and incubators of cultivated plant varietal diversity: the case of fig (Ficus carica L.) in Morocco" ppsx
Ngày tải lên :
12/08/2014, 03:21
... diversity, is a signature of a genetic equilibrium situation, with no trace of a past colonization process This feature and the quasi-absence of widespread varieties, is suggestive of a cultivation ... significance of population differentiation was estimated using exact tests [45] To assess genetic isolation by distance, spatial genetic structure was investigated using a spatial autocorrelation ... was assessed within site when there was any hint of a doubt, and systematically, among sites Local variety names were noted as given by farmers; photographs and GPS coordinates were recorded as...
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translation as cultural transfer the case of translating idioms of food and drink = dịch thuật như sự chuyển đổi về văn hóa ứng dụng trong việc dịch thành ngữ về đồ ăn thức uống
Ngày tải lên :
28/02/2015, 11:54
... that anyone can it is easy as beans If something is easy as pie, it is very easy indeed (UK) If something is easy peasy, it is very easy indeed ('Easy peasy, lemon squeezy' is also used.) If someone ... may bear a literal meaning and an idiomatic 31 meaning So what is said can be understood as the literal meaning and what is implicitly communicated is the idiomatic meaning However, when translating ... sometimes be omitted altogether in the target text This may be because it has no close match in the target language, its meaning cannot be easily paraphrased, or for stylistic reasons 5) Strategy of...
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Translation as cultural transfer the case of translating idioms of food and drink
Ngày tải lên :
10/08/2015, 19:52
... political stabilization and equality That, the need of understanding between people and nations has increased Translation constitutes an essential tool for better communication, better understanding ... International Translation Bureau™ (2003), Frequently asked questions: What is translation Retrieved April 25, 2006, from http://www.itbtranslation.com/faqs.html Karamanian, A. P (January, 2002), Translation ... nature of culture, culture in relation with language and translation Later, the chapter presents an overview of translation theories developed by well-known authors with certain basic theoretical items...
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